SURFACE INTERFACE ONTARIO

"CREATING PARTNERSHIPS FOR INNOVATIVE RESEARCH"

Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS)


Applications


Molecular Information

 

Imaging

 

Depth Information

 

Principal Component Analysis (PCA)

 

Region of Interest Analysis - confirms presence


Heating - Cooling

Surface study of collagen/poloxamine hydrogels by ToF-SIMS to confirm mechanism of cell attachment

  • Necessary to freeze-sample to "lock" hydrogen structure in vacuum.

  • Sample frozen to -130°C and warmed to -95°C to remove water.

  • ToF-SIMS spetra indicative of polymer in its hydrated state.